江维教授

生命科学学院

电子邮箱

瀚海星云BBS

CMI杂志

图书馆VIP

首页教授风采教授风采

江维教授

( 2020-05-27 )

实验室网站：http://lirst.ustc.tsg211.com/

江维 教授，博导，2011年加入免疫所。国家高层次人才特殊支持计划科技创新领军人才，基金委优青获得者。2007年毕业于图书馆VIP，获理学博士学位；2007至2011年于瑞士Ludwig肿瘤学研究所从事博士后研究；2011年加入免疫所。在Cell、Nat Immunol、Nat Rev Immunol、Immunity、J Exp Med和Nat Commun等国际高水平杂志发表篇论文30余篇，他引2000余次。获2019年度国家自然科学二等奖（第二完成人）。2004年10月回国受聘为图书馆VIP生命科学学院教授，细胞信号传导及基因调控实验室项目负责人。

主要研究兴趣：危险信号和肠道共生微生物的免疫识别和疾病机制研究。

近期发表论文：

1. Xu Y, Yan J, Tao Y, Qian X, Zhang C, Yin L, Gu P, Liu Y, Pan Y, Tang R, Jiang W, Zhou R. Pituitary hormone α-MSH promotes tumor-induced myelopoiesis and immunosuppression. Science. 2022 Sep 2;377(6610):1085-1091. doi: 10.1126/science.abj267

2. Wang X, Cai J, Lin B, Ma M, Tao Y, Zhou Y, Bai L, Jiang W, Zhou R. GPR34-mediated sensing of lysophosphatidylserine released by apoptotic neutrophils activates type 3 innate lymphoid cells to mediate tissue repair. Immunity.2021 Jun 8;54(6):1123-1136.e8

3. Huang Y, Wang H, Hao Y, Lin H, Dong M, Ye J, Song L, Wang Y, Li Q, Shan B, Jiang Y, Li H, Shao Z, Kroemer G, Zhang H, Bai L, Jin T, Wang C, Ma Y, Cai Y,Ding C, Liu S, Pan Y, Jiang W, Zhou R. Myeloid PTEN promotes chemotherapy-induced NLRP3 inflammasome activation and antitumor immunity. Nat Cell Biol. 2020 Jun;22(6):716-727.

4. Gong T, Liu L, Jiang W, Zhou R. DAMP-sensing receptors in sterile inflammation and inflammatory diseases. Nat Rev Immunol. 2020 Feb;20(2):95-112.

5. Liu L, Gong T, Tao W, Lin B, Li C, Zheng X, Zhu S, Jiang W, Zhou R. Commensal viruses maintain intestinal intraepithelial lymphocytes via noncanonical RIG-I signaling. Nat Immunol. 2019 Dec;20(12):1681-1691

6. Gong T, Zhou R. ApoC3: an 'alarmin' triggering sterile inflammation. Nat Immunol. 2020 Jan;21(1):9-11.

7. Yan Y, Jiang W, Liu L, Wang X, Ding C, Tian Z, Zhou R. Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome. Cell. 2015 Jan 15;160(1-2):62-73.

8. Wang X, Jiang W, Yan Y, Gong T, Han J, Tian Z, Zhou R. RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway. Nat Immunol. 2014 ;15(12):1126-33.

9. Yan Y, Jiang W, Spinetti T, Tardivel A, Castillo R, Bourquin C, Guarda G, Tian Z, Tschopp J, Zhou R. ω-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation. Immunity. 2013 Jun 27;38(6):1154-63.

10. Jiang H, He H, Chen Y, Huang W, Cheng J, Ye J, Wang A, Tao J, Wang C, Liu Q, Jin T, Jiang W, Deng X, Zhou R. Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders. J Exp Med 2017 Nov 6;214(11):3219-3238.